SuperShot/PRP is a treatment technique used to tighten and strengthen weak and damaged ligaments and tendons and cartilage which are believed to cause pain and instability. It is also used to decrease pain and improve function in some forms of arthritis. The technique requires the injection of Platelet Rich Plasma derived and exosomes from the patient’s own blood (autologous) according to standard blood collection and injection techniques.

Exosomes are derived from mesenchymal stem cells (MSC’s) and have similar functions such as repairing tissue damage, suppressing inflammatory responses, and modulating the immune system. Mesenchymal stem cells (MSCs) are among the most frequently used cell type in regenerative medicine for their ability to differentiate into different cell types such as cartilage cells, ligament cells, tendon cells, nerve cells, bone cells, and others.

Exosomes play important roles in cell-to-cell communication and exert positive effects on regeneration in many tissues. The exosomes isolated by SuperShot/PRP are Autologous and collected from the patient’s own Platelet-Poor Plasma. This eliminates any possible risk from commercial exosomes (allogenic exosomes) derived from someone else.

In a standard PRP preparation, whole blood is centrifuged into three components, separated by density: red blood cells, Platelet-Rich Plasma, and Platelet-Poor Plasma. In SuperShot/ PRP, the Platelet-Poor Plasma is centrifuged one additional time using the SuperShot/PRP patent-pending aqueous two-phase system, that precipitates low-density lipid-rich exosomes from the Plasma.

The exosomes isolated by SuperShot/PRP are added to the PRP, resulting significantly higher mesenchymal stem cell exosomes compared to allogeneic commercially prepared exosomes. Dependent upon each individual condition, more than one treatment may be necessary.

• Autologous: uses the patient’s own exosomes
• Nonsurgical procedure: this is an injection procedure
• More economical: commercially prepared exosomes are more expensive
• Higher number of Exosomes: a leading allogeneic mesenchymal stem cell exosome product contained just 0.6% pf the exosomes isolated by SuperShot/PRP
• Safe and easy to administer delivered in the same manner as other safe injection procedures

SuperShot/PRP is delivered in the same manner as other Regenerative Joint Injections. Due to the simplicity of the procedure, SuperShot/PRP is performed during a single office visit. Aftercare instructions are provided, and the patient drives home on their own.